*COLLINS NIMAKO¹、Anri HIRAI¹、Takahiro ICHISE¹、Shouta MM NAKAYAMA^1,2、Mayumi Ishizuka¹、Yoshinori IKENAKA^1,3,4,5 (1.Laboratory of Toxicology, Department of Environmental Veterinary Sciences, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan、2.Biomedical Sciences Department, School of Veterinary Medicine, The University of Zambia、3.Water Research Group, Unit for Environmental Sciences and Management, North-West University, Potchefstroom, South Africa、4.One Health Research Center, Hokkaido University, Hokkaido, Japan、5.Translational Research Unit, Veterinary Teaching Hospital, Faculty of Veterinary Medicine, Hokkaido University, Hokkaido, Japan)