[4E2-OS-12b] OS-12

[4E2-OS-12b-02] Proposal of Motif-wiring design method based on qualitative neural dynamics

〇YOSHIMASA TAWATSUJI^1,2, YOHEI MARUYAMA², HIROSHI YAMAKAWA^1,2 (1. The University of Tokyo, 2. Whole Brain Architecture Initiative)

Keywords:Brain Reference Architecture, Motif, Qualitative Reasoning

When designing Brain Reference Architecture, it is essential to evaluate the dynamic properties of the pre-designed neural circuits before development and implementation, as this evaluation streamlines the implementation process. One significant challenge is the incomplete neuroscientific knowledge in certain brain regions. Therefore, we need a methodology that enables system-level behavioral analysis even with partially unknown neural mechanisms. In this study, we focus on motifs, the fundamental computational units of the brain, and propose a method for analyzing the dynamic behavior inherent in the system structure using qualitative reasoning. By implementing a qualitative neurodynamics model, we achieve both model simplification and motif componentization. The simulation of these combined components enables us to predict the system-level behavior of specific neural architectures. This method is particularly valuable as it enables behavioral analysis of neural systems that include circuits with incomplete neuroscientific knowledge.