[13p-B1-1~13] English session: Joint symposium on Nanobiotechnology and Biosensing

▲ [13p-B1-12] Development of Tunnel-Current Identification by Nano-gap Device Toward Single-Molecule Electrical Sequencing

〇Takahito Ohshiro¹, Makusu Tsutsui¹, Kazumichi Yokota¹, Masateru Taniguchi¹ (1.ISIR Osaka Univ)

Keywords:DNA, Tunnel-Current, Single-Molecule Detection

Single-molecule electrical sequencing technology is one of the promising candidates for next-generation sequencers. We have proposed a single-molecule tunnel-current based detection method by using a nano-gap device and have demonstrated detections and discriminations of specific sample nucleotide and peptide. In this study, we developed the nano-gap devices integrated with molecular-control parts, and reported on the detection of nucleotide by this modification of molecular behaviors.