[13p-P6-1~6] 4 JSAP-OSA Joint Symposia 2016（Poster）

▲ [13p-P6-1] Prostate Specific Antigen Detection Using Photonic Crystal Nanocavity Resonator

〇Amrita Kumar Sana¹, Yoshiteru Amemiya¹, Takeshi Ikeda¹, Akio Kuroda¹, Shin Yokoyama¹ (1.Hiroshima Univ.)

Keywords:photonic crystal (PhC), biosensor and sensitivity, prostate specific antigen (PSA)

Prostate cancer is the 6th most common cause of cancer death overall in the world. In this work, we have developed a double nanocavity type PhC based resonator to defect the PSA marker. We have used the rapid functionalization method of photonic crystal (PhC) nanocavity resonator with antibodies using Si-tagged protein G. Since various kinds of antibody can be used as receptors for bio sensing, this method promises to realize the integrated biosensors for high-throughput analyte detection without labeling. This PhC-based sensing platform has shown a great promise in detecting PSA at the early stage of prostate infection with high sensitivity. We successfully meaured very lower concentration of 0.5 ng/ml of PSA. At this stage our device promises good agreement to detect PSA marker but it needs further measurements to make sure the device performance and its reproducibility.