[14p-P18-1~19] 12.6 Nanobiotechnology

[14p-P18-2] Observation of interactions between
various lengths of DNA molecules and a nanopore or slit

〇Seiya Minato¹, Surat Wangwarunyoo², Naoto Sakashita¹, Kentaro Ishida¹, Toshiyuki Mitsui¹ (1.Aogaku Univ., 2.Chulalongkorn Univ.)

Keywords:nanopore, DNA, Clogging

Although great progress has been made in fabricating silicon based nanopore devices, as the next generation of DNA sequencing technology, the translocation of moderately long DNA molecules cause clogging frequently at the pore. We have directly observed the interactions between DNA molecules with different-lengths and pore or slit mouths by fluorescent microscopy.