[14p-P19-1~20] 12.7 Biomedical Engineering and Biochips

[14p-P19-9] Comparison of the sugar chains for the developments of an influenza biosensor

〇Toshio Kawahara¹, Hiroaki Hiramatsu¹, Yasuo Suzuki¹, Shinichi Nakakita², Yohei Watanabe³, Yasuhide Ohno⁴, Kenzo Maehashi⁵, Takao Ono⁶, Yasushi Kanai⁶, Kazuhiko Matsumoto⁶ (1.Chubu Univ., 2.Kagawa Univ., 3.KPUM, 4.Tokushima Univ., 5.TUAT, 6.Osaka Univ.)

Keywords:Influenza virus, Bio sensor, Suger chain

Nano-carbon materials have highly potential for advanced devices because of the many superior properties such as high mobility, high strength and so forth. For nano devices, we can use field effect transistors using nano-carbon channels, and high performance sensors, noise enhanced nonlinear devices has been developed. On the other hand, Influenza is a major issue in public health [3], and we should continuously check the spreading of influenza A virus variants because of a high mutation rate of this RNA virus. Many infections to human have been reported and it might be the potential to mutate the host from bird to human. The surveillance of such mutation is highly required, and we need high sensitive sensor systems. We have developed the bio-sensor using nano-carbon materials, which can detect the preferable host by the virus. The host change can be observed as the change of the bonding between the virus protein and the host sugar chain. In this talk, we will discuss about the Comparison of the sugar chains for the developments of the influenza biosensor.