[14p-P23-1~11] English session: Joint symposium on Nanobiotechnology and Biosensing

▲ [14p-P23-3] Development of micro- and nano-structured LSPR chip for label free single cell assay

〇(D)RiyazAhmad MohamedAli¹, Masato Saito¹, Mizuho Murahashi¹, Eiichi Tamiya¹ (1.Osaka Univ.)

Keywords:LSPR, microwell, single cell

Intensive study on single cell monitoring and its secreted protein is very important to precisely observe any infectious diseases in the human body system. Microwells array becomes new versatile platform for high throughput for cell secret and continuous long-term monitoring. Thousands of individual cells can be trap within certain perimeter of area by simple gravitational sedimentation. Individual cell response from each cavity can provide important data for drug testing, toxicology and basic cell biology application. In this study, we propose label free single cell microwell array made of SU-8 as mirco-structure that integrated with gold nano structure for localized surface plasmon resonance (LSPR) application.