[15p-B7-1~18] 8.6 Plasma life sciences

△ [15p-B7-14] Effects of Physical and Chemical Stimuli Induced by In-Liquid Plasma on Cell Membrane Transport

〇Yutaro Hokari¹, Shota Sasaki¹, Makoto Kanzaki², Takehiko Sato³, Toshiro Kaneko¹ (1.Dept. of Electronic Eng., Tohoku Univ., 2.Dept. of Biomedical Eng., Tohoku Univ., 3.Inst. of Fluid Sci., Tohoku Univ.)

Keywords:in-liquid plasma, cell membrane, drug-molecule transfer

Non-equilibrium atmospheric-pressure plasma has recently emerged as a novel tool in medicine. As we assume the treatment in vivo, we try to generate the micro plasma in liquid and apply it to the transfer of the drug-simulated molecule to the cell. As a result, the drug-simulated molecules are transferred to the cells over a wide area, regardless of the electric current density. Therefore long lifetime reactive species which is enough to diffuse, could be one of key factors in cell membrane permeabilization by in-liquid plasma.