[19p-W323-1~16] 12.6 Nanobiotechnology

[19p-W323-16] Binding of Lipopolysaccharide and Cholesterol-Modified Gelatin on Supported Lipid Bilayers: Effect of Bilayer Area Confinement and Bilayer Edge Tension

〇Chiho Kataoka¹, Yoshihisa Kaizuka¹, Tetsushi Taguchi¹ (1.NIMS)

Keywords:supported lipid bilayers,supported bilayers

Binding of amphiphilic molecules (lipopolysaccharide or cholesterol-modified gelatin) to supported lipid bilayers results in lipid fibril extension or bilayer area expansion. Fibril extension occurs for confined bilayers, while area expansion is observed for unconfined bilayers. When an unconfined bilayer patch consists of a broad bilayer segment with a long thin streak, area expansion mainly occurs within the bilayer streak. In this presentation, we talk about the mechanism of fibril generation and the driving force for the non-uniform expansion of bilayer patches.