[20p-P12-1~31] 12.7 Biomedical Engineering and Biochips

[20p-P12-27] Dissolvable material-based silicon-whisker electrode packaging for in vivo recordings

〇DONGSHENG TEO¹, HIROHITO SAWAHATA¹, SHOTA YAMAGIWA¹, AIRI MORIYA¹, HIDEO OI¹, YORIKO ANDO¹, RIKA NUMANO¹, MAKOTO ISHIDA¹, KOWA KOIDA¹, TAKESHI KAWANO¹ (1.Toyohashi Univ. of Tech)

Keywords:Silicon,Neural Probe

Here we newly developed a new neural electrode device with the polyimide-based flexible printed circuit and covered with silk fibroin. FPC allows the electrode to be implanted to hard-to-reach areas such as cerebellum and sulcus, while silk fibroin, which is a biocompatible and water soluble. This device aims to acquire neuronal recording from hard-to-reach areas such as cerebellum and sulcus, by just simply slip in the highly-flexible, silk fibroin protected device into the brain. Our results suggest the feasibility of long-term recording of neuronal activity from hard-to reach brain area such as subdural and inner sulcus spaces of large animals.