[21p-W331-1~19] CS.2 3.7, 12.6, 12.7のコードシェアセッション「レーザー・ナノ・バイオ ―プロセシングとセンシングの融合に向けて―」

[21p-W331-13] Measuremet of Reactive Species for the Development of Plasma-on-Chip

呉 準席^1,2、小島 信也³、八田 章光^1,2、佐々木 実³、〇熊谷 慎也³ (1.Kochi Univ. Technol.、2.Center Nanotechnol.、3.Toyota Technol. Inst.)

キーワード：Plasma-on-Chip、UV absorption spectroscopy、Cell

Low-temperature atmospheric-pressure plasmas are getting importance in the biomedical field. To understand the interaction between the plasma and cells, we have suggested a brand new device “plasma-on-chip”. The plasma-on-chip device consists of microwells and microplasma sources which are fabricated together in a chip. Between the microwells and microplasma sources, there are micro through-holes. The plasma-on-chip device enables to culture cells in the microwells and to deliver plasma-generated reactive species to the cells through a gas-liquid interface formed at the micro through-hole(s). In the 76^th JSAP Autumn meeting, we reported the inactivation of Chlorella cells using the plasma-on-chip. It remained as an open question which plasma-generated reactive species were delivered into the microwells and inactivated the cells. In this study, we demonstrated the delivery of the reactive species by the analysis using in-situ UV absorption spectroscopy and analyzed the concentrations of reactive species.