The 78th JSAP Autumn Meeting, 2017

Presentation information

Poster presentation

12 Organic Molecules and Bioelectronics » 12.6 Nanobiotechnology

[6p-PB5-1~12] 12.6 Nanobiotechnology

Wed. Sep 6, 2017 4:00 PM - 6:00 PM PB5 (P)

4:00 PM - 6:00 PM

[6p-PB5-6] Unsaturated lipid concentration dependence for phase separation at a lipid bilayer suspended over microwells

Koki Harada1, Yuto Nakatani1, Sho Tamura1, Azusa Oshima2, Hiroshi Nakashima2, 〇Koji Sumitomo1 (1.University of Hyogo, 2.NTT BRLs.)

Keywords:Lipid bilayer, Phase separation, Raft-like structure

The localization of liquid-ordered (Lo) and liquid-crystalline (La) phase domains is investigated on a silicon substrate with a microwell array. It was known that unsaturated lipid is condensed at the suspended membrane, and saturated lipid and cholesterol are excluded. It was difficult to remain the Lo phase domain at the suspended membrane. In this study, we have tried to control the phase separation at the suspended membrane by changing the ratio of unsaturated lipid.