[7a-A502-1~12] 12.7 Biomedical Engineering and Biochips

[7a-A502-3] Hook and loop microfastener-based nerve recording device

〇Yusuke Seki¹, Shota Yamagiwa¹, Yusuke Morikawa¹, Hirohito Sawahata¹, Rika Numano¹, Kowa Koida¹, Makoto Ishida¹, Takeshi Kawano¹ (1.Toyohashi Tech.)

Keywords:cuff electrode, neural recording, flexible device

Here we propose a highly-flexible and -biocompatible parylene–based microelectrode array with a hook and loop microfastener, which realizes the electrode is stably tied to a nerve (~1 mm in diameter). Neural recording from a nerve is a way to offer safer brain-machine interface (BMI) technology, compare to that from a brain tissue. However, because a nerve is soft and small diameter geometry, attachment of an electrode device to the nerve is still problematic, resulting in unstable recording and damage to the nerve. We fabricate microscale-hook and -loop fasteners using 10-μm-thick parylene film, while an array of Pt-microelectrodes is integrated for multisite nerve recording applications. Attachment and recording capabilities of the device are demonstrated using a mouse’s peripheral nerve, confirming the device advantages of i) tunable tie position, ii) numerous diameters of ‘cuff’ of the film device, and iii) reattachable features. Such flexible microelectrode device is also applicable to numerous biological samples, including not only any nerves, but also tissues and organs.