[14a-F204-1~12] 12.7 Biomedical Engineering and Biochips

[14a-F204-4] Influence of mechanical stimulus on embryonic chick heart cell aggregates

〇Shin Arai¹, Ayaha Tsuyuki¹, Takahiro Uehara¹, Kentaro Ishida¹, Toshiyuki Mitsui¹ (1.Aogaku Univ.)

Keywords:beat, cardiac, mechano

Electrical-mechanical coupling between cardiac cells in the heart has received considerable attention in order to regulate the heartbeat. However, direct mechanical stimuli on beating cardiac aggregates in a dish has not been applied to observe its effects. We present stabilized cardiac beat activity in 24 h by a stimulus after abnormal beat sequence, likely related to arrhythmia.