[16a-P7-1~13] English session: Joint Symposium on Nanobiotechnology and Biosensing

▲ [16a-P7-2] Membrane Domains at Fusion Process of Proteoliposomes into Supported Lipid Bilayer

〇Ryugo Tero¹, Kohei Fukumoto¹, Miyu Yoshida², Ayumi Hirano-Iwata², Michio Niwano² (1.Toyohashi Tech., 2.Tohoku Univ.)

Keywords:lipid bilayer, membrane proteins, atomic force microscope

Membrane fusion is one of key processes in material and signal transport into and out of cells. We investigated fusion of proteoliposomes, crude membrane extracts from CHO and HEK293 cells, into supported lipid bilayer systems using fluorescence microscope and atomic force microscope. Microdmains in lipid bilayers were key factors in the fusion process.