[17a-F206-1~12] 12.6 Nanobiotechnology

△ [17a-F206-12] Manipulation of Lipid Bilayers Using Virtual Cathode Display

〇(DC)Hiroki Miyazako^1,2, Kunihiko Mabuchi¹, Takayuki Hoshino¹ (1.Univ. of Tokyo, 2.JSPS Research Fellow (DC1))

Keywords:lipid bilayer, electron beam lithography, virtual cathode

We propose local and reversible manipulation technique of lipid bilayers using virtual cathode display. By irradiating an electron beam (EB) to a 100-nm-thick silicon nitride (SiN) membrane, a focused electric field can be controlled two-dimensionally, and this electric field can generate mechanical stress such as Maxwell stress and osmotic pressure. In this study, we demonstrated reversible shape transformation of a lipid tube into a chain of vesicles by EB irradiations.