[20a-221C-1~10] 12.7 Biomedical Engineering and Biochips

▲ [20a-221C-2] Single 5 µm diameter multifunctional neuroprobe block module devices

〇Nurliyana Tajudin¹, Kento Onozaki¹, Shota Yamagiwa¹, Hirohito Sawahata², Takeshi Kawano¹ (1.Toyohashi Tech, 2.AIST)

Keywords:Optogenetics

In advance neuroscience, optogenetics offers an enormous potential for the future especially to study about brain. Through this method, excitation and silencing of cells can be simply performed by light with high precision in a reversible manner. In the previous research done by our group, we had overcome the limitations of conventional waveguide devices for optogenetics through the fabrication of the three-dimensional platinum/silicon dioxide microtube arrays that consists of both optical stimulating micro-scale light source and electrical recording site in the same alignment. However, the size of the device (8 x 8 mm²) substrate is relatively large to approach various cortical areas as in vivo is a priority, particularly when it comes to test on animals (e.g., rodents). To achieve the miniaturization of the device, here we fabricate a single microtube with a 5 µm diameter on a 1 x 1 mm² block module. In addition, the microtube block module can be assembled into numerous device package. Here we discussed about the fabrication process and the optical transmission test of the device.