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[17a-A202-1] Control of DNA Translocation through GeSbTe Nanopore by Laser Heating
Keywords:nanopore, DNA sensing, thermophoresis
The lower thermal conductivity of chalcogenide glass material Ge2Sb2Te5 is potentially available for generating localized-thermal distribution in a solvent. We previously reported that the thermal property of Ge2Sb2Te5 provided thermal and long-range transportation of polystyrene beads diffused in a 2D micro-fluid channel due to heat convection induced by localized-thermal distribution. A long-range transportation technology has long been desired for biological applications. In this work, we demonstrate a noble application of Ge2Sb2Te5 to a nanopore sensor device. Nanopore is a nano-scaled hole on a thin silicon membrane used as a nano-fluid device. Translocation of proteins and DNA molecules through a nanopore and measuring ionic current blockades or fluorescence signals allows single molecule measurements due to its extremely high spatial resolution. Here, we report that the combination of Ge2Sb2Te5 and nanopore reduced the event rate of DNA translocation by thermal transport called Soret effect while an optical measurement with a lower applied voltage.