[18p-P5-1~22] 12.6 Nanobiotechnology

[18p-P5-13] Observation of DNA’s anomalous dynamics near nano-scale pores

〇(B)Tomoya Kubota¹, Naoto Sakashita¹, Seiya Minato¹, Yoshiki Herai¹, Toshiyuki Mitsui¹ (1.Aogaku Univ.)

Keywords:DNA, nanopoe, electroosmotic flow

The high-speed sequencing devices using nanopores are promising. However, sequencing long DNA’s is still challenging because such DNA’s clog in a pore. We have investigated interactions between a pore and a DNA, causing the clog using fluorescence microscopy. Our recent results indicated the electroosmosis by DNA itself. To elucidate it, the dynamics of DNA of different length was investigated.