2:00 PM - 2:15 PM
[18p-E202-5] Molecular-Charge-Contact-Based Ion-Sensitive Field-Effect Transistor Sensor in Microfluidic System for Biomacromolecular Recognition
Keywords:macrobiomolecule, semiconductor
In demand of the recently aging society, the development of medical diagnostic technologies is becoming increasingly important. Among various biosensors, a field-effect transistor (FET)-based biosensor has a potential to realize next-generation diagnostics, owing to its unique feature of the potentiometric methodology.
In our previous study, the molecular charge contact (MCC) method has been used to move biomacromolecular charges to enter the Debye length without controlling the spatial distribution of beads. In this study, a microfluidics system was combined with the MCC-based ISFET sensor, as an attempt to suppress the potential response based on the interference of biomolecules in biosamples, for a clinical sample detection in the future.
In our previous study, the molecular charge contact (MCC) method has been used to move biomacromolecular charges to enter the Debye length without controlling the spatial distribution of beads. In this study, a microfluidics system was combined with the MCC-based ISFET sensor, as an attempt to suppress the potential response based on the interference of biomolecules in biosamples, for a clinical sample detection in the future.