[19p-E215-1~17] 4.5 Terahertz Photonics

▲ [19p-E215-16] Detection of lung cancer cells using a terahertz chemical microscope

〇Kosuke Sato¹, Masahiro Iida¹, Hirofumi Inoue², Toshihiko Kiwa¹, Shinichi Toyooka², Keiji Tsukada¹ (1.Graduate School of Interdisciplinary Science and Engineering in Health Systems, Okayama Univ., 2.Graduate School of Medicine Dentistry and Pharmaceutical science, Okayama Univ.)

Keywords:terahertz, cancer, semiconductor

A cancer genome therapy is one kind of the precision medicine, which is an idea to analyze a patient’s genetic information and optimize medical treatment for each patient. To evaluate the analyzed tissue includes the information of the cancer gnome, quantitative evaluation of the ratio of cancer cells to normal cells in the tissue is required. However, evaluation conventionally takes more than two days because formalin fixed paraffin embedded (FFPE) blocks are firstly prepared, which was followed by dyeing.
In our group, we have proposed and developed a terahertz chemical microscope (TCM) to detect specific cancer cells using immune-reaction of cancer cells. The TCM potentially can detect cancer cells without any pretreatment, so that rapid evaluation of the ratio of cancer cells to normal cell in the tissue can be realized. We have demonstrated the detection of breast cancer cells using the TCM.