[19p-PB9-1~24] 12.6 Nanobiotechnology

[19p-PB9-13] Mechanisms underlying bioinertness of zwitterionic peptide-based self-assembled monolayers

〇Ryongsok Chang¹, Taito Sekine¹, Aki Kashiwazaki², Daiki Murakami², Masaru Tanaka², Tomohiro Hayashi^1,3 (1.Tokyo Tech, 2.Kyushu Univ., 3.JST-PRESTO)

Keywords:bioinertness, zwitterionic peptide-based SAM, surface force measurement

In this work, we report the evaluation of bioinertness of zwitterionic peptide-based self-assembled monolayers (SAMs) by protein adsorption and cell adhesion tests. Moreover, we analyze the interaction by interfacial molecules and ions between the zwitterionic peptide-SAMs by surface force measurements. From these results, we discuss the mechanisms underlying bioinertness of the zwitterionic peptide-SAMs.