[20a-E305-1~10] 2.3 Application, radiation generators, new technology

[20a-E305-6] Demonstration of small animal Compton imaging using a WGI prototype

〇Hideaki Tashima¹, Eiji Yoshida¹, Hidekatsu Wakizaka¹, Miwako Takahashi¹, Kotaro Nagatsu¹, Atsushi Tsuji¹, Kei Kamada², Katia Parodi³, Taiga Yamaya¹ (1.NIRS-QST, 2.C&A Corp., 3.LMU)

Keywords:Whole Gamma Imaging, Positron Emission Tomography, Compton imaging

Our proposed WGI combining PET and Compton imaging (Compton camera) techniques by inserting a scatterer ring into a PET detector ring enables imaging of single gamma nuclides with wide range of energy. In this stury, we demonstrated Compton imaging of a small animal by a previously developed prototype modified for the small animal study. We injected 9.8 MBq ⁸⁹Zr-oxalate, which emits both positron and single gamma ray with energy of 909 keV, to a healthy mouse and measured by the WGI prototype for 1-hour long, 22 hours after the injection. An image obtained by the Compton imaging mode was similar to an image obtained with the PET mode, indicating that the Compton imagin mode was able to depict distribution of the tracer assimilating in the bone. The demonstration showed the ability of WGI to image single gamma nuclides.