[20p-E306-1~14] 8.4 Plasma life sciences

▲ [20p-E306-6] Mechanism of Aqueous Reactions in Non-equilibrium Atmospheric Pressure Plasma-activated Lactec Solutions

〇(M2)Yang Liu¹, Kenji Ishikawa¹, Hiroshi Hashizumi¹, Hiromasa Tanaka¹, Takayoshi Tsutsumi¹, Hiroki Kondo¹, Makoto Sekine¹, Masaru Hori¹ (1.Nagoya Univ.)

Keywords:aqueous reaction, plasma activated lactate

Non-equilibrium atmospheric pressure plasma (NEAPP) activated lactated Ringer’s solution (PAL) induces the selective killing effects of cancer cells. [1] Reactive oxygen nitrogen species (RONS), such as H₂O₂ and nitrite [2], as well as reactive organic substances, such as pyruvic acid, glyoxylic acid and 2,3-dimethyl tartrate, were detected in PAL.[3] However, aqueous reactions of the reactive organics generation have not been clarified in details so far. In this study, we have analyzed the NEAPP-induced chemical reactions in regard with lactate by using various methods, such as electron spin resonance (ESR), colorimetric methods, nuclear magnetic resonance (NMR), and gas chromatography-mass spectrometry (GC-MS).