[10p-Z03-1~7] Frontier of Research on Mechanism of Plasma-induced Biological Reactions

[10p-Z03-1] Cancels : Understanding and application of the biological function of the glycosylation by through the low-temperature atmospheric pressure plasma technology

Sanae Ikehara¹, Yoshihiro Akimoto², Takashi Yamaguchi¹, Hajime Sakakita³, Masaru Hori⁴, 〇Yuzuru Ikehara^1,3 (1.Chiba Univ., 2.Kyorin Univ., 3.AIST, 4.Nagoya Univ.)

Keywords:low-temperature atmospheric-pressure plasma, protein aggregations, glycosylation

My research career had begun with the discovery of a cancer-associated glycan that appears in gastric cancer and a sialyltransferase gene that synthesizes STn antigen [11], proceeding to drug delivery technology using glycan functions and development of glycobiomarkers [2, 12-15]. Now, our research is in the new stage where we can try to modify the biological roles of glycosylation by changing electric statues of proteins and tissues using plasma technology because we have already reached a stage being able to apply plasma technology for the alternating pathophysiological condition. In the symposium, we would like to introduce and discuss this new area that combines plasma science with glycobiology.