[10p-Z28-1~21] 3.4 Biomedical optics

[10p-Z28-8] Scanning Measurements of Cancerous Tissues with Circularly-Polarized Light

〇Nozomi Nishizawa¹, Al-Qadi Bassam², Takahiro Kuchimaru³, Hiro Munekata¹ (1.FIRST, Tokyo Tech., 2.Palestine Tech. Unv., 3.Jichi Med. Univ.)

Keywords:Biosensing, Circularly polarized light, Cancer diagnosis

The polarization of light multiply scattered by biological tissues against incident circular polarization (CP) has been considered as a powerful tool for the diagnosis of tumor tissue, particularly pre-cancerous lesions. It is reported that the polarization state of scattered light against incident circular polarization can discriminate between ablated cancerous and non-cancerous tissue in vitro with the incident light with λ = 639 nm. Based on these reports, we proposed a non-staining, non-invasive and in-vivo cancer diagnosis technique using spin-LEDs which can directly emit and detect circularly polarized light. We have investigated the applicability of scattered CP light with Monte Carlo Simulations. Experimentally reported in this paper is the in-plane distribution and angle dependences of polarization of light scattered by sliced biological tissues using circularly polarized light with λ ~ 900 nm.