[12a-A407-1~11] 12.6 Nanobiotechnology

[12a-A407-9] Single-particle mass spectrometry using a low-aspect-ratio nanopore

〇Makusu Tsutsui¹, Kazumichi Yokota¹, Akihide Arima¹, Yuhui He², Tomoji Kawai¹ (1.Osaka Univ., 2.Huazhong Univ.)

Keywords:nanopore, viscous drag, single-particle dynamics

Low-aspect-ratio nanopore is a versatile sensor capable of counting and identifying single-particles and molecules of variable sizes by means of simple two-probe elecrtical current measurements. In my talk, I will talk about our recent experimental findings that the low-aspect-ratio nanopores can be used to measure not only volume and shape of single-nanoparticles but even their sub-picogram mass.