[12p-A408-1~7] 12.7 Biomedical Engineering and Biochips

△ [12p-A408-4] High-efficiency molecular delivery into adhesive cells via artificial tunneling nanotubes

〇(M1)Kazuhiro Oyama¹, Dinuo Zheng¹, Bowen Zhang¹, Kohei Sahara¹, Takeo Miyake¹ (1.Waseda Univ, IPS)

Keywords:Artificial nanotube, Cell, Bioelectronics

In our laboratory, we are working on the development of technology to efficiently introduce substances into cells by making Au-made artificial TNT and inserting artificial TNT into cells. The applicant has been working on the development of technologies for fabricating Au nanotubes of various sizes using this technique and injecting substances into cells via the nanotubes. In this paper, we report that the efficiency of transfection of low-molecular-weight calcein and protein was improved to more than 90% by using the system using this nanotube.