[13p-A408-1~16] 12.7 Biomedical Engineering and Biochips

△ [13p-A408-14] Needle electrode with an amplifier for extracellular in vivo recordings

〇(M1)Yu Seikoba¹, Yuto Kita¹, Shuhei Tsuruhara¹, Hiroshi Kubo¹, Hirohito Sawahata², Shota Yamagiwa¹, Koji Yamashita¹, Shinnosuke Idogawa¹, Xian Long Angela Leong¹, Rika Numano¹, Kowa Koida¹, Takeshi Kawano¹ (1.Toyohashi Univ., 2.NIT, IC)

Keywords:Si micro needle, MOSFET, Neuroral recording

We propose a single needle-topped amplifier package, so called STACK device, for use in a low invasive and a high signal-to-noise ratio neuronal recording from brain in vivo. The device includes two advantages: i) device minimization and ii) simplified on-chip MOS amplifier integration. The STACK device can be simply assembled by stacking three components: microneedle-electrode module, MOSFET amplifier module, and flexible interposer. The overall device geometry is ~ 1 × 1 mm², which size is applicable to a small brain, such as mice. The microneedle with a high impedance characteristic shows the signal-amplitude attenuation, which is clearly improved by stacking the amplifier module. We also confirmed the neuronal recording capability of the STACK device, as demonstrated in the recording using a mouse’s brain in vivo.