The 67th JSAP Spring Meeting 2020

Presentation information

Oral presentation

8 Plasma Electronics » 8.4 Plasma life sciences

[14a-A304-1~9] 8.4 Plasma life sciences

Sat. Mar 14, 2020 9:00 AM - 11:30 AM A304 (6-304)

Satoshi Uchida(Tokyo Metropolitan Univ.)

10:45 AM - 11:00 AM

[14a-A304-7] Induction of stress-responsive MAPK activity by radical-activated medium for melanoma cells

〇(M2)Kazuma Ogawa1, Yuki Hori1, Miki Tanaka1, Murata Tomiyasu1, Tanaka Hiromasa2, Hori Masaru2, Ito Masafumi1 (1.Meijo Univ., 2.Nagoya Univ.)

Keywords:plasma, radical, stress-responsive MAPK

We have prepared a radical-active culture solution (RAM) using a radical source and examined its effect on melanoma cells. The results showed that RAM induced apoptosis based on oxidative stress and endoplasmic reticulum stress. <o:p></o:p>In this study, we investigate phosphorylation of p38 and JNK using Western blotting and the correlation with cell death was measured using inhibitors to verify whether the induction of RAM cell death in melanoma cells was induced by the stress-responsive MAPK.<o:p></o:p>