[10p-S402-1~18] 12.7 Biomedical Engineering and Biochips

△ [10p-S402-14] Patch-type device for transepidermal potential monitoring with microneedle

〇Ryohei Takizawa¹, Yuina Abe¹, Shuhei Yamaguchi², Yuki Tatsui², Hiroya Abe^1,3, Matsuhiko Nishizawa^1,2 (1.Graduate School of Engineering, Tohoku Univ., 2.Graduate School of Biomedical Engineering, Tohoku Univ., 3.FRIS, Tohoku Univ.)

Keywords:transepidermal potential, microneedle, Ag/AgCl electrode

Transepidermal potential (TEP) is a potential difference generated in the epidermal layer. It has been reported that the value of the TEP changes with the status of the skin barrier function, and the TEP is a useful indicator of skin health status. In this study, the objective was to measure the TEP for a long time in a minimally invasive method. We developed a patch-type device consisting of a tip-open porous microneedle made by patterned coating of parylene C and a Ag/AgCl electrode made by screen printed. In addition, we succeeded in measuring the TEP of a human participant for 8 hours using the patch-type device.