[13p-N322-1~16] 12.7 Biomedical Engineering and Biochips

▲ [13p-N322-16] Design and Development of Molecularly Imprinted Polymer Membrane for Electrochemical Determination of Stress Biomarkers in Biological Fluids

〇(D)Arpit Goyal¹, Toshiya Sakata¹ (1.The Univ. of Tokyo)

Keywords:biosensors, molecularly imprinted polymers, electrochemistry

Cortisol is a steroid hormone and a known biomarker for stress. Quantitative detection of cortisol can diagnose stress related disorders in the early stages. In this presentation, we explore the development of a non-enzymatic molecular imprinted polymer based on reduced graphene oxide and beta-cyclodextrin as a sensor electrode for electrochemical detection of cortisol in biological samples. Cyclodextrin and its ability to create host-guest interactions are used for the recognition of Cortisol, which enhances the selectivity of the MIP. The method and materials discussed can be used as a template for developing sensors for other biomarkers.