[18p-Z22-1~15] 12.7 Biomedical Engineering and Biochips

△ [18p-Z22-9] Development of high definition insertable pH image sensor with integrated electrode for electroencephalogram recording

〇(B)Mai Madokoro¹, Kotaro Sakamoto¹, Yasuyuki Kimura¹, Tomoko Horio¹, Yong Joon Choi¹, Kazuhiro Takahashi¹, Toshihiko Noda¹, Kazuaki Sawada¹ (1.Toyohashi Univ. of Tech.)

Keywords:pH imaging, Bio sensor, In-vivo sensor

A high definition insertable pH image sensor with integrated electrode for electroencephalogram recording was developed to observe the behavior of H+ in each cell and record electrode for electroencephalogram at the same time. As a result of the evaluation experiment, the cutoff frequency of the electroencephalograph was 100 kHz and the standard deviation of the output voltage fluctuation was 0.0823 mV, which satisfied the required specifications. The sensor detected the change of hydrogen ion distribution in the insertion experiment using two layers of test objects having different pH. From this result, we thought that it would be possible to observe the hydrogen ion distribution in vivo with high definition and record the electrode for electroencephalogram at the same time.