11:00 〜 11:30
▲ [20a-C304-6] [INVITED] Plasmonic waveguiding single-cell endoscopy
キーワード：plasmonic, single-cell endoscopy
Silver nanowires (AgNWs) serve as plasmonic waveguides for propagating surface plasmon polaritons (SPPs), allowing the spatial confinement and transfer light energy over micrometer distance through the structures below sub-diffraction limited diameter. In addition to this, surface plasmon allows us to concentrate light energy in nanometer regions, such as at the nanowire end, leading to a massive enhancement of electromagnetic filed that can be used for surface enhanced Raman scattering (SERS) or fluorescence (SEF) spectroscopy/microscopy.
In this contribution, we will discuss a noble nanoscopic techniques using a combination of SERS/SEF detection and sub-diffraction limit SPPs waveguiding for spectroscopic/microscopic. Specifically, we demonstrate that SPPs launched along a AgNW can remotely excite SERS [1] and SEF [2] in the vicinity of the nanowire surface due to the SPPs wave-guiding effect. The ability to transfer SERS/SEF excitation over several microns will be discussed with respect to single-cell endoscopy, understanding of interaction between anti-cancer drug molecules and cellular components such as DNA for drug delivery systems [3], and surface characterization using tip-enhanced Raman/fluorescence microscopy [4].
References:
[1] H. Uji-i et al., Analytical Chemistry, 2021, 93, 12, 5037–5045. Advanced Materials, 2014. 26, 5124-5128. Nano Lett., 2009, 9, 995 - 1001.
[2] H. Uji-i et al, Nature Commun. 2015, 6, 6287.
[3] H. Uji-i et al, Sci. Rep., 2019, 9, 2666.
[4] H. Uji-i et al, Nanoscale, 2022. 14, 5439 - 5446
In this contribution, we will discuss a noble nanoscopic techniques using a combination of SERS/SEF detection and sub-diffraction limit SPPs waveguiding for spectroscopic/microscopic. Specifically, we demonstrate that SPPs launched along a AgNW can remotely excite SERS [1] and SEF [2] in the vicinity of the nanowire surface due to the SPPs wave-guiding effect. The ability to transfer SERS/SEF excitation over several microns will be discussed with respect to single-cell endoscopy, understanding of interaction between anti-cancer drug molecules and cellular components such as DNA for drug delivery systems [3], and surface characterization using tip-enhanced Raman/fluorescence microscopy [4].
References:
[1] H. Uji-i et al., Analytical Chemistry, 2021, 93, 12, 5037–5045. Advanced Materials, 2014. 26, 5124-5128. Nano Lett., 2009, 9, 995 - 1001.
[2] H. Uji-i et al, Nature Commun. 2015, 6, 6287.
[3] H. Uji-i et al, Sci. Rep., 2019, 9, 2666.
[4] H. Uji-i et al, Nanoscale, 2022. 14, 5439 - 5446