[21p-B200-1~13] Applied Physics to controll cell fate: Innovation by plasma science and biotechnology

[21p-B200-3] Molecular and Gene Transfection by Spontaneous Cytosis Triggered by the Plasma Complex Stimuli

〇Masafumi Jinno^1,3, Yoshihisa Ikeda¹, Hideki Motomura¹, Yugo Kido², Susumu Satoh^1,3 (1.Ehime Univ., 2.Pearl Kogyo Co. Ltd., 3.i-Gene Co.)

Keywords:plasma gene transfection, random genome integrattion-free, gene transfer

In 2002, a phenomenon was discovered in which giant molecules such as plasmids are introduced into cells by applying discharge plasma to the cells. Since then, research on "plasma gene transfection" has been conducted both in the world. The authors have been working to elucidate the mechanism of this phenomenon and to put it to practical use. In the presentation we introduce the mechanism of the micro-plasma and surface discharge methods that we have developed and their applications.