[22p-A102-1~17] 2.4 Medical application

[22p-A102-6] Experimental comparison of relative stopping power evaluation between low-energy proton CT and X-ray CT for pre-clinical proton therapy researches based on small animals

〇Atsuki Terakawa¹, Hibiki Hosokawa², Kenta Shigihara², Ai Kajiyama², Yoshihiko Fujise², Rina Nagao², Keiichiro Narumi², Hiroyuki Hosokawa², Mitsuhiro Nogami², Mitsuhiro Fujiwara², Seiichi Wada³, Nobumichi Nagano², Keitaro Hitomi² (1.CYRIC, Tohoku Univ., 2.Eng. Tohoku Univ., 3.Kitasato Univ.)

Keywords:proton therapy, low-energy proton CT, relative stopping power

Accurate treatment planning is essential not only for high-precision proton therapy but also for proton therapy researches based on small animals to precisely deliver proton dose in vary small target volumes. In this study, we derived relative stopping powers (RSP) used in the treatment planning for tissue-equivalent and water-equivalent phantoms with known constituent elements using proton CT (pCT) at 73.65 MeV, which is dedicated to proton irradiation of small animals, and evaluated RSP accuracy and the advantages of the low-energy pCT over XCT.