[22p-A105-1~20] 12.7 Biomedical Engineering and Biochips

△ [22p-A105-6] A study on flow in microfluidic devices for biosensor integration

〇(M2)Yuya Takahashi¹, Kotaro Kamitani¹, Carl Frederik Werner¹, Minoru Noda¹ (1.Kyoto Inst. Tech.)

Keywords:microfluidics, micro-TAS, biosensor

A microfluidic device adaptable to array sensors for the simultaneous detection with different phospholipid species of liposomes and different recognition molecules in multiple sensor cells was developed. In this study cantilever sensors are integrated with the microfluidic device. Since these are mechanical sensors, they are possibly influence by the solution flow. In this study, the influence of flow on the microfluidic sensor system is investigated mainly by using fluid velocity simulations and actual measurements.
Fluid flow simulations were performed under laminar flow conditions to study the behavior of the fluid in the channel on a 3D model designed with dimensions equivalent to those of the channel to be used. It was observed that the velocity distribution near the cantilever tip was reduced by moving the position of the inlet from directly above the cantilever to the side of fixed end of cantilever.