[22p-A106-1~15] 12.6 Nanobiotechnology

[22p-A106-2] Detection of Candida Mannan with a Plasmonic Sensor Chip: Study of Immobilization Method for Capture Antibody

〇(M1)Masaya Yako¹, Seika Shimizu¹, Keiko Tawa¹, Hiroshi Kurita² (1.Kwansei Gakuin Univ., 2.Shinshu Univ.)

Keywords:plasmon, biosensor

Today, measurement of Candida Mannan (CM) takes several days, and a rapid detection is required. In our laboratory, CM has been measured with a plasmon-enhanced fluorescent immunosensor using a plasmonic chip, which is a substrate with a wavelength-size periodic structure on its surface and coated with a thin metal film. In this study, we investigated the immobilization method of the capture antibody and aimed to sensitively detect CM in solution and oral Candida in saliva.