The 69th JSAP Spring Meeting 2022

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11 Superconductivity » 11.4 Analog applications and their related technologies

[23a-D214-1~7] 11.4 Analog applications and their related technologies

Wed. Mar 23, 2022 9:00 AM - 11:00 AM D214 (D214)

Toshihiko Kiwa(Okayama Univ.), Yoshimi Hatsukade(Kindai Univ.)

10:15 AM - 10:30 AM

△ [23a-D214-5] Evaluation of Magnetic Properties of Magnetic Nanoparticles in Blood Using HTS-SQUID Magnetic Immunoassay System

〇Kei Yamashita1, Misaki Tsubota1, Kouhei Kishimoto1, Hiroto Kuroda1, Jin Wang1, Kenji Sakai1, Toshihiko Kiwa1 (1.Okayama Univ.)

Keywords:Superconducting Quantum Interference Device, Magnetic nanoparticles, Magnetic Immunoassay

The magnetic properties of magnetic nanoparticles(MNP), which are superparamagnetic and unique to MNP, have been used in the development of magnetic immunoassays for the specific detection of proteins by antigen-antibody reactions. However, the magnetic properties of MNP have been shown to be affected by biological substances. In this study, we measured the time variation of the third harmonic of MNP in sheep blood using the developed HTS-SQUID magnetic immunoassay system. The results showed that the magnetic signal decreased with time in the blood.