2022年第69回応用物理学会春季学術講演会

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一般セッション(口頭講演)

12 有機分子・バイオエレクトロニクス » 12.7 医用工学・バイオチップ

[24a-E105-1~10] 12.7 医用工学・バイオチップ

2022年3月24日(木) 09:00 〜 11:45 E105 (E105)

野田 俊彦(豊橋技科大)、加治佐 平(東洋大)

11:30 〜 11:45

[24a-E105-10] Design and Development of Host-Guest Interaction-Based Molecularly Imprinted Polymer Membrane for Electrochemical Determination of Stress Biomarkers in Biological Fluids

〇(D)Arpit Goyal1、Toshiya Sakata1 (1.The Univ. of Tokyo)

キーワード:biosensors, molecularly imprinted polymer, electrochemistry

Cortisol is a steroid hormone and a known biomarker for stress. Quantitative measurement of cortisol can diagnose chronics stress and other disorders in the early stages. In this presentation, we investigate the development of a non-biological molecular imprinted polymer (MIP) biosensor based on reduced graphene oxide, beta-cyclodextrin, polypyrrole as a sensor electrode for electrochemical detection and determination of cortisol in biological samples. Cyclodextrin and its ability to create host-guest interactions, coupled with imprinted polypyrrole MIP, are used for recognition and measurement of cortisol. The method and materials discussed can be used as a template for developing affordable and point-of-care sensors for other biomarkers.