[24p-E104-1~16] CS.8 Code-sharing Session of 12.6 & 12.7

[24p-E104-10] Development of amino acid analysis by single molecule detection method with nanogap devices

〇Takahito Ohshiro¹, Yuki Komoto¹, Taniguchi Masateru¹ (1.Osaka University)

Keywords:single-molecule detection, Tunnel-Current, amino acid

Single-molecule quantum measurements using a nanogap electrode device were used to obtain conductance-time profile signal for single amino acid molecules including their L- and D-form molecules. The obtained electrical signals reflect the characteristic electrical conductivity of the translocation/interaction behaviors between the gap electrodes. By using our machine learning based on these signals, we succeeded in the discrimination of amino acid species with high discrimination ability. In addition, we have also succeeded in discriminating these amino acid species in a mixed solution of amino acid by this developped method.