[26p-E204-1~13] 3.4 Biomedical optics

[26p-E204-8] Brain tumor screening from infrared absorption spectrum of plasma

〇Saiko Kino¹, Naoki Oda¹, Masayuki Kanamori², Kuniyasu Niizuma², Teiji Tominaga², Yuji Matsuura¹ (1.Graduate School of Biomedical Engineering, Tohoku Univ., 2.Graduate School of Medicine, Tohoku Univ.)

Keywords:mIR-ATR spectroscopy, Plasma screening, PLSR

A basic study was conducted with the aim of screening for brain tumors from blood. Absorption spectra of plasma samples from brain tumor patients and healthy subjects were obtained using mid-infrared attenuation total reflection (ATR) spectroscopy, which does not require sample pretreatment and is highly sensitive. When the measurement protocol for obtaining equal and stable spectra in each sample was determined and the two groups were compared, a clear difference was found. Furthermore, by multivariate analysis of the spectrum, a discriminant that can identify the diseased person was obtained.