Yoko Miura¹, Ken-ichi Nagakura¹, Noriyuki Yanagida¹, Sakura Sato², Motohiro Ebisawa² (1.Department of Pediatrics, National Hospital Organization Sagamihara National Hospital, Japan, 2.Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Japan)

Mayu Maeda, Takanori Imai, Toshinori Nakamura, Kosei Yamashita, Toshiyuki Takagi, Yuki Okada, Taro Kamiya, Katsumi Mizuno (Department of pediatrics, Showa University School of Medicine, Japan)

Nobuhiro Nakano¹, Toshiyuki Yoneyama², Mutsuko Hara¹, Hiromichi Yamada², Kumi Izawa¹, Koichiro Uchida¹, Ayako Kaitani¹, Tomoaki Ando¹, Jiro Kitaura¹, Yoshikazu Ohtsuka², Toshiaki Shimizu², Hideoki Ogawa¹, Ko Okumura¹ (1.Atopy (Allergy) Research Center, Juntendo University Graduate School of Medicine, Japan, 2.Department of Pediatrics and Adolescent Medicine, Juntendo University Graduate School of Medicine, Japan)

Christine YY Wai¹, Ka Hou Chu², Patrick SC Leung³, Ting Fan Leung¹ (1.Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, 2.School of Life Sciences, The Chinese University of Hong Kong, Hong Kong, 3.Division of Rheumatology/Allergy, School of Medicine, University of California, USA)

Yu Kuwabara^1,4,6, Mizuho Nagao^1,4, Sayami Ito², Naoki Okada², Mio Saito³, Ying-Shu Quan³, Fumio Kamiyama³, Komei Ito⁴, Motohiro Ebisawa^4,5, Yuichi Adachi⁴, Makoto Kameda⁴, Shigemi Yoshihara⁴, Akira Hoshioka⁴, Mizue Tsukui⁴, Yusei Oshima⁴, Hirokazu Arakawa⁴, Naoki Shimojo⁴, Naoka Itoh⁴, Takao Fujisawa^1,4 (1.National Hospital Organization Mie National Hospital, Japan, 2.Project for Vaccine and Immune Regulation, Graduate School of Pharmaceutical Sciences, Osaka University, Japan, 3.CosMED Pharmaceutical Co. Ltd, Japan, 4.AMED Ebisawa reserach group, Japan, 5.National Hospital Organization Sagamihara National Hospital, Japan, 6.Department of Pediatrics, Ehime University Graduate School of Medicine, Japan)