Oral Session

[O7] Oral Session 7"Viral vectors 3"

Tue. Sep 12, 2023 2:20 PM - 3:20 PM Room 3 (1008, 10Ｆ, OICC)

Chairs:Ko Mitani（Saitama Medical University）,Toshiro Shirakawa（Kobe University Graduate School of Science, Technology and Innovation, Division of Advanced Medical Science）

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[O7-1] Development of PSMA-targeted Oncolytic Adenovirus for Treatment of Prostate Cancer

^○Mizuho Sato-Dahlman, Praveen Hajeri, Kari Jacobsen, Chikako Yanagiba, Masato Yamamoto (University of Minnesota)

[O7-2] Aggregation analysis and testing for residual gag/pol DNA fragment as quality testing for retroviral vector used for TBI-2001 manufacturing

^○Naoki Matsushita¹, Shinya Tanaka¹, Toshikazu Nishie¹, Nobuto Koyama¹, Takahiro Maruno², Masanori Noda², Takaaki Kurinomaru², Susumu Uchiyama², Maki Tanaka¹ (1.TAKARA BIO INC., 2.U-Medico Inc.)

[O7-3] Development of cyclic peptide ligand installed ternary complex to improve tumor selectivity of Adeno Associated Virus (AAV)

^○Nozomi Matsudaira^1,2, Yuto Honda^1,2, Shuhei Nagao^1,2, Hiroaki Kinoh³, Yutaka Miura^1,2, Nobuhiro Nishiyama^1,2 (1.Tokyo Institute of Technology School of Life Science and Technology Department of Life Science and Technology, 2.Tokyo Institute of Technology Laboratory for Chemistry and Life Science Institute of Innovative Research, 3.KAWASAKI INSTITUTE OF INDUSTRIAL PROMOTION Innovation Center of NanoMedicine)

[O7-4] Improvement of human adenovirus serotype 35 vector for vaccine application

^○Rika Onishi¹, Sena Ikemoto¹, Aoi Shiota¹, Tomohito Tsukamoto¹, Masashi Tachibana¹, Fuminori Sakurai¹, Hiroyuki Mizuguchi^1,2,3,4,5 (1.Grad. Sch. of Pharm. Sci., Osaka Univ., 2.NIBIOHN, 3.OTRI, Osaka Univ., 4.MEI cent., Osaka Univ., 5.CiDER, Osaka Univ.)

[O7-5] A recombinant adenovirus vector containing the synNotch receptor gene inhibits tumor growth of bladder cancer in a mouse xenograft model

^○RUHAN A¹, Koichi Kitagawa¹, Erika Hirata¹, Masato Fujisawa², Toshiro Shirakawa² (1.Kobe University Graduate School of Science, 2.Kobe University Graduate School of Science)

[O7-6] Creation of receptor-targeting AAV capsids by LassoGraft: in vivo efficacy, endowment of blood-brain barrier permeability, and development of a receptor exploration method

^○Satoshi Watanabe¹, Tsuyoshi Sato¹, Yumi Sano¹, Emiko Mihara¹, Hiroaki Suga², Junichi Takagi¹ (1.Laboratory for protein synthesis and expression, Institute for Protein Research, Osaka University, 2.Department of Chemistry, Graduate School of Science, The University of Tokyo)