Naoki Itokawa¹, Motohiko Oshima¹, Yaeko Nakajima-Takagi¹, Kazumasa Aoyama¹, Satoshi Yamazaki², Atsushi Iwama¹ (1.Department of Cellular and Molecular Medicine, Chiba University., 2.The Institute of Medical Science, the University of Tokyo)

Makoto Kobayashi¹, Isao Kobayashi², Junya Tamaoki¹ (1.Faculty Med., Univ. Tsukuba, Tsukuba, Japan, 2.Faculty Natural System, Kanazawa Univ., Kanazawa, Japan)

Yuichiro Nakata¹, Takeshi Ueda², Kenichiro Ikeda¹, Norimasa Yamasaki¹, Hiroaki Honda³ (1.RIRBM, Hiroshima University, Hiroshima, Japan, 2.Department of Biochemistry, Kindai University, Osaka, Japan,, 3.Institute of Laboratory Animals, Tokyo Women's Medical University, Tokyo, Japan)

Yasuyuki Sera¹, Yuichiro Nakata², Takeshi Ueda³, Kenichiro Ikeda², Kouhei Kobatake², Norimasa Yamasaki², Hiroaki Honda¹ (1.Institute Of Laboratory Animals, Tokyo Women's Medical University, Tokyo, Japan, 2.Department of Disease Model, RIRBM, Hiroshima University, Hiroshima, Japan, 3.Department of Biochemistry, Faculty of Medicine, Kinki University, Osaka, Japan)

Akihiko Numata^1,2, Koichi Akashi¹, Tenen Daniel² (1.Hematolgy&Oncolcogy&Cardiovasuclar Medicine, Kyushu Univ. Hosp., Fukuoka, Japan, 2.Cancer Science Institute of Singapore, Singapore)

Takayuki Hoshii, Scott Armstrong (Dana-Farber Cancer Institute, Boston, MA USA)