Masao Kobayashi¹, Shiho Nishimura¹, Maiko Shimomura¹, Shinobu Sasaki¹, Naoya Yamasaki², Teruhisa Fujii² (1.Department of Pediatrics, Hiroshima University Hospital, Hiroshima, Japan, 2.Division of blood transfusion)

Shinobu Tatsunami¹, Kagehiro Amano², Akira Shirahata³, Masashi Taki⁴ (1.Unit of Medical Informatics, St. Marianna University, Kawasaki, Japan, 2.Department of Laboratory Medicine, Tokyo Medical University Hospital, Japan, 3.Kitakyushu Yahata-higashi Hospital, Kitakyushu, Japan, 4.Department of Pediatrics, St. Marianna University Seibu Hospital, Yokohama, Japan)

Kiyotaka Isobe, Jun Noguchi, Masahiro Sugawa, Nasato Yanagi, Makiko Mori, Yuki Arakawa, Katsuyoshi Koh (Department of Hematology/Oncology, Saitama Children's Medical Center, Saitama, Japan)

Hiroki Horiuchi¹, Kenichi Ogiwara¹, Keiji Nogami¹, Takehisa Kitazawa², Midori Shima¹ (1.Pediatrics, Nara Medical University, Nara, Japan, 2.Research Division, Chugai Pharmaceutical Co., Ltd,)

Midori Shima¹, Johnny Mahlangu², Johannes Oldenburg³, Takashi Suzuki⁴, Yasuharu Nishida⁵, Tadashi Matsushita⁶, Toshihiro Ito⁷, Masashi Taki⁸, Katsuyuki Fukutake⁹, Ido Paz-Priel¹⁰, Claude Negrier¹¹, Markus Niggli¹², Maria Elisa Mancuso¹³, Christophe Schmitt¹², Victor Jime'Nez-Yuste¹⁴, Christine Kempton¹⁵, Christophe Dhalluin¹², Michael Callaghan¹⁶, Willem Bujan¹⁷, Joanne I. Adamkewicz¹⁰, Elina Asikanius¹², Sayaka Nagami¹⁸, Wataru Ohtsuka¹⁸, Koichiro Yoneyama¹⁸, Ryu Kasai¹⁸, Gallia G. Levy¹⁰, Rebecca Kruse-Jarres¹⁹ (1.Pediatrics, Nara Med Univ., Kashihara, Japan, 2.University of the Witwatersrand and NHLS, Johannesburg, South Africa, 3.Universitaetsklinikum Bonn, Bonn, Germany, 4.Department of Blood Coagulation, Ogikubo Hospital, Tokyo, Japan, 5.Division of Infectious Disease, NHO Osaka National Hospital, Osaka, Japan, 6.Department of Transfusion Medicine, Nagoya University Hospital, Nagoya, Japan, 7.Dep. of infect. dis., NHO Sendai National Hospital, Sendai, Japan, 8.Pediatrics, St. Marianna University School of Medicine, Kawasaki, Japan, 9.Labo-Med., Tokyo Med., Univ., Tokyo, Japan, 10.Genentech Inc, South San Francisco, California, USA, 11.Louis Pradel University Hospital, Lyon, France, 12.F. Hoffmann-La Roche Ltd, Basel, Switzerland, 13.Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy, 14.Hematology Department, Hospital Universitario La Paz, Auto'noma University, Madrid, Spain, 15.Emory School of Medicine, Atlanta, USA, 16.Children's Hospital of Michigan, Detroit, MI, USA, 17.Instituto Costarricense de Investigaciones Cienti'ficas, San Jose', Costa Rica, 18.Chugai Pharmaceutical co., ltd., Tokyo, Japan, 19.Washington Center for Bleeding Disorders, Seattle, WA, USA)

Katsuyuki Fukutake¹, Steven Pipe², Victor Jimenez-Yuste³, Akira Ishiguro⁴, Takanori Teshima⁵, Amy Shapiro⁶, Nigel Key⁷, Maria Podolak-Dawidziak⁸, Cedric Hermans⁹, Peerlinck Kathelijne¹⁰, Michaela Lehle¹¹, Sammy Chebon¹¹, Agnes Portron¹¹, Nives Selak Bienz¹¹, Sayaka Nagami¹², Wataru Ohtsuka¹², Koichiro Yoneyama¹², Ryu Kasai¹², Gallia G. Levy¹³, Midori Shima¹⁴ (1.Labo-Med., Tokyo Med., Univ., Tokyo, Japan, 2.University of Michigan, C.S. Mott Children's Hospital, Ann Arbor, USA, 3.Hospital Universitario La Paz, Auto'noma University, Madrid, Spain, 4.Division of Hematol, NCCHD, Tokyo, Japan, 5.Hematol., Hokkaido Univ., Tokyo, Japan, 6.Indiana Hemophilia and Thrombosis Center, Indianapolis, USA, 7.University of N Carolina, Chapel Hill, North Carolina, USA, 8.Medical University Department of Hematology, Wroclaw, Poland, 9.UZ Leuven Gasthuisberg, Leuven, Belgium, 10.Cliniques Universitaires St-Luc, Brussels, Belgium, 11.F. Hoffmann-La Roche Ltd, Basel, Switzerland, 12.Chugai Pharmaceutical co., ltd., Tokyo, Japan, 13.Genentech Inc., South San Francisco; USA, 14.Pediatrics, Nara Med Univ. Kashihara, Japan)