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Koji Nagafuji¹, Takayuki Ishikawa², Hiroyuki Takamatsu³, Kenshi Suzuki⁴, Jianping Wang⁵, Robin Carson⁶, Wendy Crist⁶, Ming Qi⁷, Tomoaki Fujisaki⁸ (1.Division of Hematology and Oncology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan, 2.Department of Internal Medicine, Division of Immuno-Hematology, Kobe General Central Hospital, Kobe, Japan, 3.Hematology/Respiratory Medicine, Kanazawa University, Kanazawa, Japan, 4.Japanese Red Cross Medical Center, Department of Hematology, Tokyo, Japan, 5.Janssen Research & Development, LLC, Raritan, United States of America, 6.Janssen Biotech, Horsham, United States of America, 7.Janssen Research and Development, LLC, Spring House, United States of America, 8.Department of Internal Medicine, Matsuyama Red-Cross Hospital, Matsuyama, Japan)