Oral Session 3-10C MPN: Basic (2)

[OS3-10C-6] Homomultimerization of mutant calreticulin is required for MPL-binding and -activation

Marito Araki¹, Yinjie Yang², Misa Imai^2,3, Yoshihisa Mizukami^2,4, Yoshihiko Kihara^2,3, Yoshitaka Sunami², Nami Masubuchi^2,5, Yoko Edahiro², Yumi Hironaka², Satoshi Osaga⁶, Akimichi Ohsaka¹, Norio Komatsu² (1.Dept. Transfus. Med. & Stem Cell Reg., Juntendo Univ., Tokyo, Japan, 2.Dept. Hemat., Juntendo Univ., Tokyo, Japan, 3.Lead. Cent. Dev. Res. Cancer Med., Juntendo Univ., Tokyo, Japan, 4.Cent. Genom. & Regen. Med., Juntendo Univ., Tokyo, Japan, 5.Res. Inst. Disease Old Age, Juntendo Univ., Tokyo, Japan, 6.Clin. Res. Man. Cent., Nagoya City Univ. Hosp., Nagoya, Japan)