Oral Session 3-9B MM: BM microenvironment

[OS3-9B-2] Mechanisms of TAK1 activation in myeloma cells and TAK1-mediated myeloma growth and bone destruction

Jumpei Teramachi^1,2, Hirofumi Tenshin^1,3, Masahiro Hiasa^1,3, Asuka Oda¹, Bat-Erdene Ariunzaya¹, Takeshi Harada¹, Masami Iwasa¹, Shiro Fujii¹, Kimiko Sogabe¹, Shingen Nakamura¹, Hirokazu Miki⁴, Masahiro Oura¹, Kumiko Kagawa¹, Itsuro Endo^1,5, Toshio Matsumoto⁶ (1.Department of Hematology, Endocrinology and Metabolism, Tokushima University , Japan, 2.Tissue Regeneration, Tokushima University, Japan, 3.Orthodontics and Dentofacial Orthopedics, Tokushima University, Tokushima, Japan, 4.Transfusion Medicine and Cell Therapy, Tokushima University Hospital, Tokushima, Japan, 5.Chronomedicine, Tokushima University, Tokushima, Japan, 6.Fujii Memorial Institute of Medical Sciences, Tokushima University, Tokushima, Japan)