[SY5-1] Cancer predisposition syndromes in children with cancer
Christian Kratz, MD, is full professor in Pediatrics and Director of the Department of Pediatric Hematology and Oncology, Hannover Medical School. After obtaining his medical degree in 1996 from the University of Dsseldorf, Germany, he completed his training to become a pediatrician and pediatric hematologist/oncologist in Dsseldorf, San Francisco (UCSF), and Freiburg. From 2009-2012 he worked as an investigator at the Division of Cancer Epidemiology and Genetics at the National Cancer Institute (Director: J. Fraumeni). His research focuses on the genetic causes of childhood cancer. He chairs the German Fanconi Registry and the Genetic Cancer Predisposition Working Group of the German Society of Pediatric Hematology and Oncology. Together with Stefan Pfister he has launched a Registry for patients with Li-Fraumeni syndrome and other cancer predisposition syndromes (cancer-predisposition.org). One of his most important discoveries was the identification of KRAS germline mutations in patients with Noonan syndrome. He chairs the German branch of the Li Fraumeni Syndrome Association (lfsassociation.org).
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